DocumentCode :
2499253
Title :
Single- and multi-unit activity recorded from the surface of the dorsal root ganglia with non-penetrating electrode arrays
Author :
Gaunt, Robert A. ; Bruns, Tim M. ; Crammond, Donald J. ; Tomycz, Nestor D. ; Moossy, John J. ; Weber, Douglas J.
Author_Institution :
Dept. of Phys. Med. & Rehabilitation, Univ. of Pittsburgh, Pittsburgh, PA, USA
fYear :
2011
fDate :
Aug. 30 2011-Sept. 3 2011
Firstpage :
6713
Lastpage :
6716
Abstract :
Non-penetrating surface electrode recording techniques are typically associated with field potential recordings, while extracellular recordings from single neurons are made using penetrating metal wire or microfabricated microelectrode arrays. Here, we report on single- and multi-unit neuronal recordings made using non-penetrating electrodes placed on the epineural surface of the dorsal root ganglia (DRG). Across four experiments in anesthetized cats, approximately 40% of the electrodes recorded single- and multi-unit spiking activity with spike-rates that covaried significantly with hindlimb movement. In two intraoperative experiments in humans, compound activity was recorded from the DRG surface in response to peripheral stimulation of the common peroneal nerve. This approach may have advantages over penetrating electrode arrays in terms of clinical acceptability and recording longevity.
Keywords :
bioMEMS; biomedical electrodes; microelectrodes; neurophysiology; DRG; common peroneal nerve; dorsal root ganglia surface; epineural surface; field potential recording; microfabricated microelectrode arrays; multiunit neuronal activity recording; nonpenetrating electrode arrays; penetrating metal wire; single neuron extracellular recordings; single unit neuronal activity recording; Animals; Arrays; Histograms; Humans; Microelectrodes; Signal to noise ratio; Action Potentials; Animals; Cats; Electric Stimulation; Electrodes; Electrophysiology; Ganglia, Spinal; Humans; Microelectrodes; Models, Neurological; Muscles; Neurons; Reproducibility of Results; Robotics; Surface Properties;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
ISSN :
1557-170X
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2011.6091655
Filename :
6091655
Link To Document :
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