Title :
Comparison for Antitumor Activities of Some Chinese Medicinal Herb Extracts
Author :
Juan Li ; Keli Chen ; Binghong Yang ; Xin Yu
Author_Institution :
Key Lab. of TCM Resource & TCM Compound, Hubei Coll. of Traditional Chinese Med., Wuhan, China
Abstract :
The anti-tumor activities of six medical plants (Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Herba Duchesneae Indicae, Herba Solani Lyrati, Rhizoma Smilacis Glabrae, Rhizoma Paridis Chinensis), commonly used as antitumor drugs, have been submitted to tests of MTT, Flow cytometry (FCM), DNA laddering analysis and caspase-3 expression using Bel-7402, HT-29 and HeLa cell lines. Total alkaloids and total glycosides extracts from Rhizoma Paridis Chinensis showed stronger action on inhibiting proliferation and inducing apoptosis of tumour cells.
Keywords :
biochemistry; biological techniques; botany; cellular biophysics; drugs; tumours; Bel-7402 cell line; Chinese medicinal herb extracts; DNA laddering analysis; Duchesneae indicae; HT-29 cell line; HeLa cell line; Lobeliae chinensis; MTT; Paridis chinensis; Scutellariae barbatae; Smilacis glabrae; Solani lyrati; antitumor activities; antitumor drugs; caspase-3 expression; flow cytometry; total alkaloid extracts; total glycoside extracts; Cancer; Digestive system; Diseases; Drugs; Educational institutions; In vitro; In vivo; Lungs; Medical treatment; Tumors;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5162537
