Title :
Component Vector method and Its Application in Detecting Similarities between Sequences
Author :
Duan, Guang-You ; Gao, Shan ; ZHANG, Ning ; YANG, Zhuo ; ZHANG, Tao
Author_Institution :
Key Lab. of Bioactive Mater., Nankai Univ., Tianjin, China
Abstract :
With the increase of sequence information, many methods have been used in detecting sequence similarities. In order to avoid the shortcomings of the traditional method based on sequences alignment such as high time and space complexity, component vector method has been successfully used in the reconstruction of phylogenetic tree using genome (proteome) or conserved molecular sequences. With the aim of extension and study the advantage of the method, it has been employed to detect similarities between common short gene and protein sequences and get some good results. Results show that component distance method successfully detects the similarities in our HIV sequences, and have high correlation with the traditional method based on sequence alignment.
Keywords :
biological techniques; genetics; genomics; microorganisms; molecular biophysics; proteins; proteomics; vectors; HIV sequences; component distance method; component vector method; conserved molecular sequences; gene sequence; genome; high-time complexity; phylogenetic tree reconstruction; protein sequence; proteome; sequence alignment; sequence information; space complexity; Amino acids; Bioinformatics; Biological materials; Biomedical materials; DNA; Educational institutions; Frequency; Genomics; Proteins; Sequences;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5162547