Title :
The effects of voluntary, involuntary, and forced exercises on motor recovery in a stroke rat model
Author :
Ke, Zheng ; Yip, Shea-Ping ; Li, Le ; Zheng, Xiao-Xiang ; Tam, Wing-Kin ; Tong, Kai-Yu
Author_Institution :
Dept. of Health Technol. & Inf., Hong Kong Polytech. Univ., Hong Kong, China
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
Stroke rehabilitation with different exercise paradigms has been investigated, but a comparison study on motor recovery after voluntary, involuntary, and forced exercises is limited. The current study used a rat brain ischemia model to investigate the effects of voluntary wheel running, involuntary muscle movement caused by functional electrical stimulation (FES), and forced treadmill exercise on motor recovery and brain BDNF changes. The results showed that voluntary exercise is the most effective intervention in upregulating the hippocampal BDNF level, and facilitating motor recovery after brain ischemia.
Keywords :
biomechanics; brain models; diseases; neurophysiology; patient rehabilitation; exercise paradigms; forced exercises; functional electrical stimulation; hippocampal BDNF; involuntary exercises; involuntary muscle movement; motor recovery; rat brain ischemia model; stroke rat model; stroke rehabilitation; voluntary exercises; voluntary wheel running; Brain modeling; Educational institutions; Hippocampus; Muscles; Rats; Wheels; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Male; Motor Activity; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Recovery of Function; Stroke;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6092028
