Title :
Carbon nanotubes for inducing magnetotactic properties into cells
Author :
Pensabene, V. ; Marino, M. ; Menciassi, A. ; Dario, P.
Author_Institution :
Humanoid Technol., Italian Inst. of Technol., Genoa
Abstract :
In this paper we present a method to make cells magnetotactic by using carbon nanotubes (CNTs). The key of the method consists of a highly biocompatible dispersion of CNTs. These CNTs, once added to culture medium of neuroblastoma cells, strongly interact with the cell membrane. CNTs-conjugated cells appear to be sensitive to applied magnetic field gradient and move towards the magnetic source. A simple model of the forces acting on the CNTs-conjugated cells is presented and examples of possible applications are provided, such as cell separation, magnetic force-based tissue engineering and advanced imaging techniques.
Keywords :
biomagnetism; biomembranes; cancer; carbon nanotubes; cellular biophysics; nanobiotechnology; neurophysiology; tissue engineering; C; carbon nanotubes; cell membrane; cell separation; magnetic field gradient; magnetic force-based tissue engineering; magnetotactic properties; neuroblastoma cells; Carbon nanotubes; Cells (biology); Immune system; Iron; Magnetic properties; Magnetic separation; Marine technology; Microorganisms; Nanoparticles; Robots;
Conference_Titel :
Biomedical Robotics and Biomechatronics, 2008. BioRob 2008. 2nd IEEE RAS & EMBS International Conference on
Conference_Location :
Scottsdale, AZ
Print_ISBN :
978-1-4244-2882-3
Electronic_ISBN :
978-1-4244-2883-0
DOI :
10.1109/BIOROB.2008.4762849