Title :
An integrated open-cavity system for magnetic bead separation and manipulation
Author :
Abu-Nimeh, Faisal T. ; Salem, Fathi M.
Author_Institution :
Dept. of Electr. & Comput. Eng., Michigan State Univ., East Lansing, MI, USA
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
Superparamagnetic beads are generally used in biomedical assays to manipulate, maneuver, separate, and transport bio-materials. We present a low-cost integrated system designed in bulk 0.5μm process to automate the manipulation and separation process of magnetic beads. The system consists of an 8×8 coil-array suitable for a single bead manipulation, or collaborative manipulation using pseudoparallel executions. The size of a single coil is 30μm × 30μm and the driver DC current source supports 8 different levels up to 1.5mA. The total power consumption of the entire system is 9mW when running at full power and it occupies an area of 248μm × 248μm.
Keywords :
biological fluid dynamics; biomagnetism; biomedical materials; lab-on-a-chip; magnetic particles; molecular biophysics; superparamagnetism; biomaterial; biomedical assay; collaborative manipulation; integrated open cavity system; low cost integrated system; magnetic bead manipulation; magnetic bead separation; pseudoparallel execution; superparamagnetic bead; CMOS integrated circuits; Coils; Decoding; Magnetic flux; Magnetic hysteresis; Magnetic separation; Switches; Computer Simulation; Electricity; Electronics; Finite Element Analysis; Magnetics; Metals; Microspheres; Oxides; Semiconductors; Video Recording;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6092069
