Optofluidic on-chip tomography

Author

Isikman, Serhan O. ; Bishara, Waheb ; Zhu, Hongying ; Ozcan, Aydogan

Author_Institution

Electr. Eng. Dept., Univ. of California, Los Angeles, CA, USA

fYear

2011

fDate

Aug. 30 2011-Sept. 3 2011

Firstpage

8463

Lastpage

8466

Abstract

The first demonstration of optofluidic tomography is presented. Using partially coherent illumination, holograms of objects are recorded at multiple viewing angles, as they flow through a microfluidic channel placed directly on the top of an opto-electronic sensor array. These lensfree holograms are then digitally processed to compute pixel super-resolved tomograms of micro-objects to achieve sectional opto-fluidic imaging on a chip.

Keywords

biomedical engineering; biomedical optical imaging; integrated optoelectronics; lab-on-a-chip; micro-optomechanical devices; microfluidics; optical tomography; lensfree hologram; microfluidic channel; microobject images; multiple viewing angle; optoelectronic sensor array; optofluidic on-chip tomography; optofluidic tomography; partially coherent illumination; pixel super resolved tomogram; Image reconstruction; Lighting; Microfluidics; Microscopy; Optical microscopy; Tomography; Animals; Caenorhabditis elegans; Holography; Image Processing, Computer-Assisted; Lenses; Light; Microfluidic Analytical Techniques; Microscopy; Optics and Photonics; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE

Conference_Location

Boston, MA

ISSN

1557-170X

Print_ISBN

978-1-4244-4121-1

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2011.6092088

Filename

6092088