Title :
Optofluidic on-chip tomography
Author :
Isikman, Serhan O. ; Bishara, Waheb ; Zhu, Hongying ; Ozcan, Aydogan
Author_Institution :
Electr. Eng. Dept., Univ. of California, Los Angeles, CA, USA
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
The first demonstration of optofluidic tomography is presented. Using partially coherent illumination, holograms of objects are recorded at multiple viewing angles, as they flow through a microfluidic channel placed directly on the top of an opto-electronic sensor array. These lensfree holograms are then digitally processed to compute pixel super-resolved tomograms of micro-objects to achieve sectional opto-fluidic imaging on a chip.
Keywords :
biomedical engineering; biomedical optical imaging; integrated optoelectronics; lab-on-a-chip; micro-optomechanical devices; microfluidics; optical tomography; lensfree hologram; microfluidic channel; microobject images; multiple viewing angle; optoelectronic sensor array; optofluidic on-chip tomography; optofluidic tomography; partially coherent illumination; pixel super resolved tomogram; Image reconstruction; Lighting; Microfluidics; Microscopy; Optical microscopy; Tomography; Animals; Caenorhabditis elegans; Holography; Image Processing, Computer-Assisted; Lenses; Light; Microfluidic Analytical Techniques; Microscopy; Optics and Photonics; Tomography;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6092088
