Factors Affecting the Bioaccessibility of Polychlorinated Biphenyls Using In Vitro Test

Author

Yu, Yingxin ; Han, Shuyuan ; Li, Junling ; Zhang, Dongping ; Wu, Minghong ; Sheng, Guoying ; Fu, Jiamo

Author_Institution

Inst. of Environ. Pollution & Health, Shanghai Univ., Shanghai, China

fYear

2009

fDate

11-13 June 2009

Firstpage

1

Lastpage

4

Abstract

Factors affecting the bioaccessibility of PCBs in food matrix during digestion were investigated using a static in vitro digestion model simulating human gastrointestinal (GI) tract. The results showed that the ratios of digestive juice to the mass of food (L/M), the pH values of the digestive juice and the ageing time of PCBs in food matrix had significant effect on it. The PCBs bioaccessibility increased with the L/M ratio and the pH values increasing, while it decreased with the ageing time prolong. The present study provides basic information for advanced in vitro studies on the bioaccessibility of PCBs in human body.

Keywords

ageing; organic compounds; pH; L/M ratio; ageing time; bioaccessibility; digestive juice; food mass; human gastrointestinal tract; pH; polychlorinated biphenyls; static in vitro digestion model; Absorption; Aging; Animals; Gastrointestinal tract; Humans; In vitro; In vivo; Powders; Testing; Transmission line matrix methods;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on

Conference_Location

Beijing

Print_ISBN

978-1-4244-2901-1

Electronic_ISBN

978-1-4244-2902-8

Type

conf

DOI

10.1109/ICBBE.2009.5162846

Filename

5162846