Title :
Frequency-domain analysis of arterial blood pressure: a probe for central nervous system activity
Author :
Kresh, J.Y. ; McVey, M.J. ; Frasch, H.F. ; Pelleg, A. ; Brockman, S.K.
Author_Institution :
Dept. of Cardiothoracic Surg. & Med., Hahnemann Univ., Philadelphia, PA, USA
Abstract :
Spontaneous, self-sustained arterial blood pressure oscillations (APO; Mayer-rhythm) were studied in dogs exposed to hypotension, hemorrhage, hypoxia, or cerebral ischemia. Frequency spectra analysis of APO revealed a large amplitude (15-30 mmHg), low frequency (0.04-0.06 Hz) component. Higher frequency peaks (f>0.1 Hz) of much lower power amplitude were associated with respiratory activity. These experimental pathophysiologic states resulted in the loss of broadband frequency spectra (observed in control studies) and the emergence of dominant bifurcating narrowband APO rhythms. The periodicities observed implicate a CNS-mediated neural pacemaker (i.e. sympathetic overdrive) in arterial pressure oscillations
Keywords :
haemodynamics; neurophysiology; 0.04 to 0.06 Hz; 15 to 30 mmHg; CNS-mediated neural pacemaker; Mayer-rhythm; arterial blood pressure; arterial pressure oscillations; broadband frequency spectra; central nervous system activity; cerebral ischemia; dogs; experimental pathophysiologic states; frequency-domain analysis; hemorrhage; hypotension; hypoxia; probe; respiratory activity; sympathetic overdrive; Arterial blood pressure; Bifurcation; Dogs; Frequency domain analysis; Hemorrhaging; Ischemic pain; Narrowband; Pacemakers; Probes; Rhythm;
Conference_Titel :
Computers in Cardiology 1991, Proceedings.
Conference_Location :
Venice
Print_ISBN :
0-8186-2485-X
DOI :
10.1109/CIC.1991.169123
