Title :
Modeling and Analysis of Liquid Penetration into Soft Material with Application to Needle-Free Jet Injection
Author :
Chen, Kai ; Zhou, Hua ; Li, Ji ; Cheng, Gary J.
Author_Institution :
Dept. of Mech. Eng., Hangzhou Dianzi Univ., Hangzhou, China
Abstract :
A mathematic model has been presented for a high speed liquid jet penetration into soft solid by a needle-free injection system. The model consists of a cylindrical column formed by the initial jet penetration and an expansion sphere due to continuous deposition of the liquid. By solving the equations of energy conservation and mass conservation, the penetration depth and the radius of the expansion sphere can be predicted. As an example, the calculation results were presented for a typical needle-free injection system injected into a silicon rubber.
Keywords :
drug delivery systems; jets; nozzles; silicone rubber; skin; energy conservation equation; expansion sphere radius; high speed liquid jet penetration; mass conservation equation; needle free jet injection; penetration depth; silicon rubber; soft material liquid penetration analysis; soft material liquid penetration modeling; soft solid; Capacitive sensors; Drug delivery; Equations; Mathematical model; Needles; Pharmaceutical technology; Rubber; Silicon; Skin; Solid modeling;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5163069