• DocumentCode
    2513578
  • Title

    Modeling and Analysis of Liquid Penetration into Soft Material with Application to Needle-Free Jet Injection

  • Author

    Chen, Kai ; Zhou, Hua ; Li, Ji ; Cheng, Gary J.

  • Author_Institution
    Dept. of Mech. Eng., Hangzhou Dianzi Univ., Hangzhou, China
  • fYear
    2009
  • fDate
    11-13 June 2009
  • Firstpage
    1
  • Lastpage
    5
  • Abstract
    A mathematic model has been presented for a high speed liquid jet penetration into soft solid by a needle-free injection system. The model consists of a cylindrical column formed by the initial jet penetration and an expansion sphere due to continuous deposition of the liquid. By solving the equations of energy conservation and mass conservation, the penetration depth and the radius of the expansion sphere can be predicted. As an example, the calculation results were presented for a typical needle-free injection system injected into a silicon rubber.
  • Keywords
    drug delivery systems; jets; nozzles; silicone rubber; skin; energy conservation equation; expansion sphere radius; high speed liquid jet penetration; mass conservation equation; needle free jet injection; penetration depth; silicon rubber; soft material liquid penetration analysis; soft material liquid penetration modeling; soft solid; Capacitive sensors; Drug delivery; Equations; Mathematical model; Needles; Pharmaceutical technology; Rubber; Silicon; Skin; Solid modeling;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
  • Conference_Location
    Beijing
  • Print_ISBN
    978-1-4244-2901-1
  • Electronic_ISBN
    978-1-4244-2902-8
  • Type

    conf

  • DOI
    10.1109/ICBBE.2009.5163069
  • Filename
    5163069