DocumentCode
2513578
Title
Modeling and Analysis of Liquid Penetration into Soft Material with Application to Needle-Free Jet Injection
Author
Chen, Kai ; Zhou, Hua ; Li, Ji ; Cheng, Gary J.
Author_Institution
Dept. of Mech. Eng., Hangzhou Dianzi Univ., Hangzhou, China
fYear
2009
fDate
11-13 June 2009
Firstpage
1
Lastpage
5
Abstract
A mathematic model has been presented for a high speed liquid jet penetration into soft solid by a needle-free injection system. The model consists of a cylindrical column formed by the initial jet penetration and an expansion sphere due to continuous deposition of the liquid. By solving the equations of energy conservation and mass conservation, the penetration depth and the radius of the expansion sphere can be predicted. As an example, the calculation results were presented for a typical needle-free injection system injected into a silicon rubber.
Keywords
drug delivery systems; jets; nozzles; silicone rubber; skin; energy conservation equation; expansion sphere radius; high speed liquid jet penetration; mass conservation equation; needle free jet injection; penetration depth; silicon rubber; soft material liquid penetration analysis; soft material liquid penetration modeling; soft solid; Capacitive sensors; Drug delivery; Equations; Mathematical model; Needles; Pharmaceutical technology; Rubber; Silicon; Skin; Solid modeling;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location
Beijing
Print_ISBN
978-1-4244-2901-1
Electronic_ISBN
978-1-4244-2902-8
Type
conf
DOI
10.1109/ICBBE.2009.5163069
Filename
5163069
Link To Document