Title :
Ionic channels in biological membranes: natural nanotubes described by the drift-diffusion equations
Author_Institution :
Dept. of Molecular Biophys. & Physiol., Rush Med. Center, Chicago, IL, USA
Abstract :
Ionic channels are proteins with a hole down their middle, natural nanotubes of great biological importance because they regulate many activities of cells in health and disease. Ionic channels have simple structure and obey the familiar drift-diffusion equations of semiconductor physics. It seems likely that higher resolution theories of computational electronics (e.g., Monte Carlo simulations) will reveal even more about how channels, and perhaps other proteins, function. Thus, the study of channels is a promising area for interdisciplinary investigation.
Keywords :
Monte Carlo methods; biodiffusion; biomembrane transport; ionic conductivity; molecular biophysics; nanostructured materials; proteins; Monte Carlo simulations; biological membranes; cells; computational electronics; drift-diffusion equations; ionic channels; nanotubes; proteins; Biology computing; Biomembranes; Calcium; Cells (biology); Molecular biophysics; Monte Carlo methods; Nanotubes; Physics; Poisson equations; Proteins;
Conference_Titel :
Computational Electronics, 1998. IWCE-6. Extended Abstracts of 1998 Sixth International Workshop on
Conference_Location :
Osaka, Japan
Print_ISBN :
0-7803-4369-7
DOI :
10.1109/IWCE.1998.742714