Title :
Similarity/Dissimilarity Analysis of DNA Sequences Based on a 3D Graphical Representation
Author :
Huang, Hailan ; Shi, Long
Author_Institution :
Sch. of Math. & Comput. Sci., Xiangtan Univ., Xiangtan, China
Abstract :
A 3D graphical representation of DNA sequence has been derived from chaos game representation of DNA sequence. The 3D graphical representation also avoids losses of information. According to classifications of four bases of DNA sequence we obtain three characteristic curves. The geometrical centers and fluctuation of three curves have been grouped into a twelve-component vector to represent the DNA sequence. The Euclidean distances among introduced vectors are applied to characterize and compare the coding sequences of the first exon of beta globin gene of 11 different species.
Keywords :
DNA; bioinformatics; chaos; computer graphics; game theory; molecular biophysics; pattern classification; 3D graphical representation; DNA base classification; DNA sequence analysis; Euclidean distance; beta globin gene; chaos game representation; dissimilarity analysis; geometrical center; similarity analysis; Bonding; Chaos; DNA computing; Databases; Eigenvalues and eigenfunctions; Fluctuations; Joining processes; Mathematics; Sequences; Sorting;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5163386
