Title :
CHARACTERIZATION OF DYSFUNCTION IN LEFT AND RIGHT TEMPORAL LOBES OF ANXIETY PATIENTS: USING SPATIOTEMPORAL LYAPUNOV EXPONENT
Author :
Hongjian, He ; Xiaoping, Xie ; Feiyan, Chen ; Xiaohu, Zhao
Author_Institution :
Dept. of Phys., Zhejiang Univ., Hangzhou
Abstract :
The dysfunction in anxiety disease has been widely observed in clinics, but the underlying neural mechanism is not yet well understood. Function MRI data were collected conventionally ´imperfectly´ with low frequency and short scans when participants were processing our experimental tasks. In order to find the nonlinear differences, we here propose the spatiotemporal Lyapunov exponent as a quantitative measure. Our result reveals that there are significant differences between the two groups. We conclude that: (1) spatiotemporal Lyapunov exponent could be used to explore nonlinear character of conventional ´imperfect´ fMRI data; (2) the abnormal nonlinear dynamic behavior exists in bilateral temporal lobes when patients are taking our experimental tasks.
Keywords :
Lyapunov matrix equations; biomedical MRI; brain; diseases; neurophysiology; anxiety disease; bilateral temporal lobes; function MRI; spatiotemporal Lyapunov exponent; Blood; Brain; Chaos; Diseases; Helium; Magnetic resonance imaging; Nonlinear dynamical systems; Physics; Spatiotemporal phenomena; Temporal lobe;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
1-4244-0672-2
Electronic_ISBN :
1-4244-0672-2
DOI :
10.1109/ISBI.2007.356879