Title :
FULLY AUTOMATED WHOLE-BODY REGISTRATION IN MICE USING AN ARTICULATED SKELETON ATLAS
Author :
Baiker, M. ; Milles, J. ; Vossepoel, A.M. ; Que, I. ; Kaijzel, E.L. ; Löwik, C. W G M ; Reiber, J.H.C. ; Dijkstra, J. ; Lelieveldt, B.P.F.
Author_Institution :
Div. of Image Process., Leiden Univ. Med. Center
Abstract :
In this paper, we propose a fully automated articulated registration approach for whole-body 3D data of mice. The method is based on a hierarchical anatomical model of the skeletal system where we specified position and degrees of freedom for each joint. Model fitting is performed by traversing a hierarchical part-tree, which enables a coarse-to-fine registration from the inner articulations outwards. The method was tested on 12 micro-CT volumes, giving accurate alignment of the skeletal structures in all cases.
Keywords :
bone; computerised tomography; image registration; medical image processing; orthopaedics; articulated skeleton atlas; automated whole-body registration; coarse-to-fine registration; mice; microCT volumes; Animals; Biomedical imaging; Bones; Diseases; Joints; Mice; Plasma welding; Skeleton; Skull; Testing;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
1-4244-0672-2
Electronic_ISBN :
1-4244-0672-2
DOI :
10.1109/ISBI.2007.356955
