Title :
A CONTINUOUS MIXTURE OF TENSORS MODEL FOR DIFFUSION-WEIGHTED MR SIGNAL RECONSTRUCTION
Author :
Jian, Bing ; Vemuri, Baba C. ; Özarslan, Evren ; Carney, Paul ; Mareci, Thomas
Author_Institution :
Dept. of Comput. & Inf. Sci. & Eng., Florida Univ., Gainesville, FL
Abstract :
Diffusion MRI is a non-invasive imaging technique that allows the measurement of water molecular diffusion through tissue in vivo. In this paper, we present a novel statistical model which describes the diffusion-attenuated MR signal by the Laplace transform of a probability distribution over symmetric positive definite matrices. Using this new model, we analytically derive a Rigaut-type asymptotic fractal law for the MR signal decay which has been phenomenologically used before. We also develop an efficient scheme for reconstructing the multiple fiber bundles from the DW-MRI measurements. Experimental results on both synthetic and real data sets are presented to show the robustness and accuracy of the proposed algorithms.
Keywords :
Laplace transforms; biomedical MRI; medical signal processing; physiological models; probability; signal reconstruction; Laplace transform; Rigaut-type asymptotic fractal; diffusion-weighted MR signal; multiple fiber bundles; non-invasive imaging; probability distribution; signal reconstruction; tensors model; water molecular diffusion; Fractals; Image reconstruction; In vivo; Laplace equations; Magnetic resonance imaging; Probability distribution; Signal analysis; Signal reconstruction; Symmetric matrices; Tensile stress;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
1-4244-0672-2
Electronic_ISBN :
1-4244-0672-2
DOI :
10.1109/ISBI.2007.356966