Three-Dimensional Digital Atlas Construction of Chinese Brains by Magnetic Resonance Imaging

This paper describes the construction of an atlas of the human brain by magnetic resonance imaging. The successive steps of the construction were performed with images acquired by three- dimensional fast spoiled gradient-echo recalled acquisition sequences in 1.5 T. Data from the young and middle-aged healthy volunteers were spatially normalized into MNI coordinate frame in SPM2 software based on MATLAB. Three-dimensional brain atlas were reconstructed in the MNI coordinate system. There atlases enable efficient structure localization and morphometric comparison, which play important roles in the computer aided surgery, image guide surgery, minimal invasive surgery and other frontier areas.