Title :
Patterns of gene deletion following genome duplication in yeast
Author :
Byrnes, Jake K. ; Li, Wen-Hsiung
Author_Institution :
Dept. of Ecology & Evolution, Chicago Univ., IL, USA
Abstract :
Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following WGD in yeast with simulations. We find that deletion events alternate between paralogous chromosomes more often than expected under a random duplicate deletion model.
Keywords :
biology computing; cellular biophysics; genetics; microorganisms; gene adjacency reorganization; gene deletion pattern; gene massive duplicate deletion; genome duplication; paralogous chromosomes; random duplicate deletion model; whole genome duplication; yeast; Bioinformatics; Biological cells; Biological system modeling; Computational modeling; Conferences; Environmental factors; Fungi; Genetics; Genomics; System testing;
Conference_Titel :
Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE
Print_ISBN :
0-7695-2442-7
DOI :
10.1109/CSBW.2005.104
