DocumentCode :
2527943
Title :
MassTRAQ: a fully automated tool for iTRAQ-labeled protein quantification
Author :
Lin, Wen-Ting ; Wu, Kuen-Pin ; Hung, Wei-Neng ; Yian, Yi-Hwa ; Chen, Yet-Ran ; Chen, Yu-Ju ; Sung, Ting-Yi ; Hsu, Wen-Lian
Author_Institution :
Inst. of Inf. Sci., Acad. Sinica, Taipei, Taiwan
fYear :
2005
fDate :
8-11 Aug. 2005
Firstpage :
157
Lastpage :
158
Abstract :
Mass spectrometry has emerged to be one of the most powerful high throughput techniques for protein analysis, and iTRAQ labeling technique is the one of the newest techniques for protein identification and quantification in this field. Here, we display a new protein abundance analysis software for iTRAQ technique called MassTRAQ that can analyze up to four sets of samples at the same time. We have analyzed two samples with expression level 1:1, and have the result of 1:1.007 with standard deviation 0.004. Thus, MassTRAQ provides a good interpretation of the protein analysis.
Keywords :
biochemistry; biological techniques; biology computing; mass spectroscopy; molecular biophysics; proteins; MassTRAQ; fully automated tool; iTRAQ labeling technique; iTRAQ-labeled protein quantification; mass spectrometry; protein abundance analysis software; protein analysis; protein identification; Amino acids; Biochemistry; Biological systems; Isobaric; Labeling; Mass spectroscopy; Peptides; Protein engineering; Protocols; Sequences;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE
Print_ISBN :
0-7695-2442-7
Type :
conf
DOI :
10.1109/CSBW.2005.89
Filename :
1540580
Link To Document :
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