DocumentCode
2527943
Title
MassTRAQ: a fully automated tool for iTRAQ-labeled protein quantification
Author
Lin, Wen-Ting ; Wu, Kuen-Pin ; Hung, Wei-Neng ; Yian, Yi-Hwa ; Chen, Yet-Ran ; Chen, Yu-Ju ; Sung, Ting-Yi ; Hsu, Wen-Lian
Author_Institution
Inst. of Inf. Sci., Acad. Sinica, Taipei, Taiwan
fYear
2005
fDate
8-11 Aug. 2005
Firstpage
157
Lastpage
158
Abstract
Mass spectrometry has emerged to be one of the most powerful high throughput techniques for protein analysis, and iTRAQ labeling technique is the one of the newest techniques for protein identification and quantification in this field. Here, we display a new protein abundance analysis software for iTRAQ technique called MassTRAQ that can analyze up to four sets of samples at the same time. We have analyzed two samples with expression level 1:1, and have the result of 1:1.007 with standard deviation 0.004. Thus, MassTRAQ provides a good interpretation of the protein analysis.
Keywords
biochemistry; biological techniques; biology computing; mass spectroscopy; molecular biophysics; proteins; MassTRAQ; fully automated tool; iTRAQ labeling technique; iTRAQ-labeled protein quantification; mass spectrometry; protein abundance analysis software; protein analysis; protein identification; Amino acids; Biochemistry; Biological systems; Isobaric; Labeling; Mass spectroscopy; Peptides; Protein engineering; Protocols; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE
Print_ISBN
0-7695-2442-7
Type
conf
DOI
10.1109/CSBW.2005.89
Filename
1540580
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