• DocumentCode
    2527943
  • Title

    MassTRAQ: a fully automated tool for iTRAQ-labeled protein quantification

  • Author

    Lin, Wen-Ting ; Wu, Kuen-Pin ; Hung, Wei-Neng ; Yian, Yi-Hwa ; Chen, Yet-Ran ; Chen, Yu-Ju ; Sung, Ting-Yi ; Hsu, Wen-Lian

  • Author_Institution
    Inst. of Inf. Sci., Acad. Sinica, Taipei, Taiwan
  • fYear
    2005
  • fDate
    8-11 Aug. 2005
  • Firstpage
    157
  • Lastpage
    158
  • Abstract
    Mass spectrometry has emerged to be one of the most powerful high throughput techniques for protein analysis, and iTRAQ labeling technique is the one of the newest techniques for protein identification and quantification in this field. Here, we display a new protein abundance analysis software for iTRAQ technique called MassTRAQ that can analyze up to four sets of samples at the same time. We have analyzed two samples with expression level 1:1, and have the result of 1:1.007 with standard deviation 0.004. Thus, MassTRAQ provides a good interpretation of the protein analysis.
  • Keywords
    biochemistry; biological techniques; biology computing; mass spectroscopy; molecular biophysics; proteins; MassTRAQ; fully automated tool; iTRAQ labeling technique; iTRAQ-labeled protein quantification; mass spectrometry; protein abundance analysis software; protein analysis; protein identification; Amino acids; Biochemistry; Biological systems; Isobaric; Labeling; Mass spectroscopy; Peptides; Protein engineering; Protocols; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE
  • Print_ISBN
    0-7695-2442-7
  • Type

    conf

  • DOI
    10.1109/CSBW.2005.89
  • Filename
    1540580