DocumentCode
2528116
Title
A parallel algorithm for clustering protein-protein interaction networks
Author
Yang, Qiaofeng ; Lonardi, Stefano
Author_Institution
Dept. of Comput. Sci., California Univ., Riverside, CA, USA
fYear
2005
fDate
8-11 Aug. 2005
Firstpage
174
Lastpage
177
Abstract
The increasing availability of interaction graphs requires new resource-efficient tools capable of extracting valuable biological knowledge from these networks. In this paper we report on a novel parallel implementation of Girvan and Newman´s clustering algorithm that is capable of running on clusters of computers. Our parallel implementation achieves almost linear speed-up up to 32 processors and allows us to run this computationally intensive algorithm on large protein-protein interaction networks. Preliminary experiments show that the algorithm has very high accuracy in identifying functional related protein modules.
Keywords
biochemistry; biology computing; molecular biophysics; pattern clustering; proteins; Girvan clustering algorithm; Newmans clustering algorithm; biological knowledge; functional related protein module; parallel algorithm; protein-protein interaction network; Availability; Bioinformatics; Biology computing; Clustering algorithms; Computer science; Concurrent computing; Fungi; Organisms; Parallel algorithms; Proteins;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE
Print_ISBN
0-7695-2442-7
Type
conf
DOI
10.1109/CSBW.2005.13
Filename
1540588
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