DocumentCode :
2532235
Title :
The effect of sequence length on DNA decorated CNT gas sensors
Author :
Liu, Y. ; Chen, M. ; Mohebbi, M. ; Wang, M.L. ; Dokmeci, M.R.
Author_Institution :
ECE, Northeastern Univ., Boston, MA, USA
fYear :
2011
fDate :
5-9 June 2011
Firstpage :
2156
Lastpage :
2159
Abstract :
This article reports the effect of deoxyribonucleic acid (DNA) sequence length on the sensing characteristics of DNA decorated single-walled carbon nanotube (SWNT) devices. First, SWNTs were assembled on micro electrodes via a versatile, solution based Dielectrophoresis process. Then four single-stranded poly-G oligomers with lengths of 8, 16, 24 and 32 were decorated on SWNTs and the response of SWNT sensors to methanol and IPA vapors were measured. We found that the optimum DNA sequence length for sensing applications was 24. Sequence length of DNA had a dramatic impact on the response of DNA-SWNT sensors. This phenomenon can be explained by the difference in binding affinities of nucleotides on SWNTs and the conformations that DNA forms on SWNTs. These experimental results have significant implications for the interactions between DNA and SWNTs. They can facilitate the development of DNA functionalized SWNT sensors in analytical chemistry, biochemistry and environmental monitoring applications.
Keywords :
DNA; biosensors; carbon nanotubes; electrophoresis; gas sensors; microelectrodes; nanobiotechnology; C; DNA conformation; DNA decorated CNT gas sensor; DNA sequence length effect; DNA-SWNT sensor; IPA vapor; analytical chemistry; binding affinity; biochemistry; deoxyribonucleic acid; dielectrophoresis; environmental monitoring; methanol; microelectrode; nucleotide; poly-G oligomer; single-walled carbon nanotube; Carbon nanotubes; Chemical sensors; DNA; Electrodes; Methanol; Resistance; Sensors; SWNT (single-walled carbon nanotube); Ss-DNA (single-stranded DNA); gas sensing; sequence length;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International
Conference_Location :
Beijing
ISSN :
Pending
Print_ISBN :
978-1-4577-0157-3
Type :
conf
DOI :
10.1109/TRANSDUCERS.2011.5969345
Filename :
5969345
Link To Document :
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