Title :
Spectral reflectance imaging biosensor for high-throughput and label-free detection of biomolecular interactions
Author :
Özkumur, Emre ; Yalçin, Ayça ; Ahn, Sunmin ; Goldberg, Bennett B. ; Chiari, Marcella ; ünlü, M. Selim
Author_Institution :
Dept. of Electr. & Comput. Eng., Boston Univ., Boston, MA, USA
Abstract :
We introduce a novel label-free microarray imaging technique and show proof-of-principle examples for biological applications. Presented technique is simple, sensitive and capable of acquiring kinetic measurements.
Keywords :
bio-optics; biomedical optical imaging; biosensors; molecular biophysics; reflectivity; biomolecular interaction; high-throughput detection; kinetic measurements; label-free microarray imaging; spectral reflectance imaging biosensor; Biomedical optical imaging; Biosensors; Fresnel reflection; Optical imaging; Optical interferometry; Optical reflection; Optical sensors; Optical surface waves; Proteins; Reflectivity;
Conference_Titel :
LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE
Conference_Location :
Belek-Antalya
Print_ISBN :
978-1-4244-3680-4
Electronic_ISBN :
1092-8081
DOI :
10.1109/LEOS.2009.5343140