Title :
Multiplexed protein detection with an array of silicon-on-insulator microring resonators
Author :
De Vos, Katrien ; Girones, Jordi ; De Koninck, Yannick ; Schacht, Etienne ; Bienstman, Peter ; Baets, Roel
Author_Institution :
Dept .of Electr. & Comput. Eng., Boston Univ., Boston, MA, USA
Abstract :
We have demonstrated simultaneous detection of multiple antibodies in a highly specific way with a novel integrated lab-on-a-chip, featuring silicon-on-insulator ring resonators, non-aggressive microfluidics packaging, receptor binding through a thin PEG layer, and camera based parallel readout.
Keywords :
biological techniques; lab-on-a-chip; micro-optics; microfluidics; optical resonators; proteins; readout electronics; silicon-on-insulator; PEG layer; camera based parallel readout; integrated lab-on-a-chip; multiple antibodies detection; multiplexed protein detection; nonaggressive microfluidics packaging; receptor binding; silicon-on-insulator microring resonator array; Microfluidics; Optical resonators; Optical ring resonators; Optical sensors; Optical surface waves; Optical waveguides; Proteins; Q factor; Resonance; Silicon on insulator technology; (130.0130) Integrated optics; (230.0230) Optical devices; (280.1415) Biological sensing and sensors;
Conference_Titel :
LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE
Conference_Location :
Belek-Antalya
Print_ISBN :
978-1-4244-3680-4
Electronic_ISBN :
1092-8081
DOI :
10.1109/LEOS.2009.5343180
