DocumentCode
2533876
Title
Optical phase to biological mass conversion for label-free interferometric sensing methods
Author
Özkumur, Emre ; Yalcin, Ayca ; Cretich, Marina ; Damin, Francesco ; Lopez, Carlos ; Bergstein, David A. ; Goldberg, Bennett B. ; Chiari, Marcella ; Ünlü, M. Selim
Author_Institution
Dept .of Electr. & Comput. Eng., Boston Univ., Boston, MA, USA
fYear
2009
fDate
4-8 Oct. 2009
Firstpage
459
Lastpage
460
Abstract
The conversion between the detected optical phase and the biological mass accumulated on the surface is determined using a label-free interferometric technique. The results demonstrate a linear phase/mass relationship for DNA and protein microarrays.
Keywords
bioMEMS; biosensors; lab-on-a-chip; light interferometry; optical sensors; proteins; DNA microarray; biological mass conversion; label-free interferometric sensing methods; label-free interferometric technique; linear phase-mass relationship; optical phase; protein microarrays; Biomedical optical imaging; Biosensors; DNA; Fluorescence; Molecular biophysics; Optical interferometry; Optical sensors; Proteins; Refractive index; Solids;
fLanguage
English
Publisher
ieee
Conference_Titel
LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE
Conference_Location
Belek-Antalya
ISSN
1092-8081
Print_ISBN
978-1-4244-3680-4
Electronic_ISBN
1092-8081
Type
conf
DOI
10.1109/LEOS.2009.5343181
Filename
5343181
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