Improvements on the detectability of glucose from spectroscopic signals

Frequent measurement of blood glucose is crucial for diabetic patients in managing the glucose level and thus reducing the severe complications associated with the disease. Raman spectroscopy is one of the non-invasive optical techniques that have been proposed for physiological glucose measurement. In this study, we used a relatively inexpensive, compact and portable Raman system which can be made sufficiently affordable and convenient for patient use. We applied two well-known linear transformation methods in a consecutive manner to the collected spectral data to improve the detectability of the glucose concentration information from aqueous solutions.