Title :
Lensfree cell holography on a chip: From holographic cell signatures to microscopic reconstruction
Author :
Isikman, Serhan ; Seo, Sungkyu ; Sencan, Ikbal ; Erlinger, Anthony ; Ozcan, Aydogan
Author_Institution :
Electr. Eng. Dept., Univ. of California, Los Angeles, CA, USA
Abstract :
We present a lensfree on-chip imaging platform that can record 2D holographic diffraction signatures of various cells for cytometry applications. We also illustrate that these lensfree cell holograms permit reconstruction of microscopic images of the same cells enabling a powerful diagnostic tool for especially global health related problems such as malaria, HIV or TB.
Keywords :
cellular biophysics; diseases; holography; lab-on-a-chip; patient diagnosis; 2D holographic diffraction; HIV; chip holography; cytometry; diagnostic tool; holographic cell signatures; lensfree cell holography; malaria; microscopic reconstruction; tuberculosis; Diffraction; Diseases; Holography; Image reconstruction; Image sensors; Lenses; Optical arrays; Optical imaging; Optical microscopy; Sensor arrays;
Conference_Titel :
LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE
Conference_Location :
Belek-Antalya
Print_ISBN :
978-1-4244-3680-4
Electronic_ISBN :
1092-8081
DOI :
10.1109/LEOS.2009.5343233
