Author :
Koch, Martin ; Weyh, Thomas ; Wolf, Bemhard
Author_Institution :
Technische Univ. Munchen, Germany
Abstract :
New dynamic markers (DM) techniques can move and spatially fix magnetically marked objects reversibly and uniquely. DM fields are independent from material constants and it can therefore be developed: magnetic field driven targeted drug delivery, detection and counting the subpopulation of cells applicable in different media. They cause macroscopic reactions by jamming microscopically into magnetic crystal lattices (beads). Thus, new diagnostic and therapeutic applications can be developed: transfection of cells in culture, destruction of thromboses, removal of atherosclerotic plaques from the arterial interior, implanted nano-scaled pumps and ventiles supplied from extracorporal energy sources.
Keywords :
biomagnetism; cellular biophysics; drug delivery systems; nanotechnology; prosthetics; arterial interior; atherosclerotic plaques removal; cell culture; cell transfection; cells subpopulation; diagnostic applications; drug delivery systems; dynamic markers; extracorporal energy sources; implanted nanoscaled pumps; implanted nanoscaled ventiles; macroscopic reaction; magnetic crystal lattices; magnetic field driven target; magnetically marked objects; microscopical jamming; therapeutic applications; thromboses destruction; Cells (biology); Crystalline materials; Delta modulation; Lattices; Magnetic fields; Magnetic force microscopy; Magnetic materials; Nanobioscience; Targeted drug delivery; Tumors;
Conference_Titel :
Nanotechnology, 2004. 4th IEEE Conference on
Print_ISBN :
0-7803-8536-5
DOI :
10.1109/NANO.2004.1392392
