Keynote address: Translating the cancer genomes

Summary form only given. Cancer is the phenotypic endpoint of myriad genetic and epigenetic aberrations that collectivey commandeer key cancer-relevant pathways. Comprehensive characterization of the cancer genome holds enormous potential to (i) provide penetrating insight into the genetic bases of cancer, (ii) identify promising candidate therapeutic targets and diagnostic biomarkers, and (iii) illuminate the path toward personalized cancer medicine. However, translating the complex cancer genomic information into biological insights that can impact in the clinic is an enormous challenge that involves multi-disciplinary collaboration from genomic, computational sciences to cancer genetics and disease biology, and clinical arenas. Importantly, such collaboration begins with and depends on accessing and visualizing the data. Examples will be shared to illustrate the importance and need for visualization.