Title :
A graphene-based microelectrode for recording neural signals
Author :
Chen, C.H. ; Lin, C.T. ; Chen, J.J. ; Hsu, W.L. ; Chang, Y.C. ; Yeh, S.R. ; Li, L.J. ; Yao, D.J.
Author_Institution :
Nat. Tsing Hua Univ., Hsinchu, Taiwan
Abstract :
We designed, fabricated and tested a novel prototype neural interface using two-dimensional single-atom-thick graphene as microelectrode for neural applications. The cytotoxicity indicated a satisfactory biocompatibility and non-toxicity. The treatment graphene with steam plasma improved the biological properties. The action potentials of lateral giant (LG) nerve fiber of the escape circuit of an American crayfish had a ratio of signal to noise (SNR) as great as 30.2±2.45 dB.
Keywords :
biomedical electrodes; biomedical materials; cellular biophysics; graphene; microelectrodes; neurophysiology; toxicology; American crayfish; C; biocompatibility; cytotoxicity; escape circuit; graphene-based microelectrode; lateral giant nerve fiber; neural applications; neural signal recording; nontoxicity; prototype neural interface; steam plasma; two-dimensional single-atom-thick graphene; Carbon; Materials; Microelectrodes; Neurons; Surface impedance; Surface treatment; Action potential; Graphene; Microelectrode; Neuron; Steam plasma;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International
Conference_Location :
Beijing
Print_ISBN :
978-1-4577-0157-3
DOI :
10.1109/TRANSDUCERS.2011.5969794
