Computer simulation of heart rate and blood pressure changes, and comparison with clinical data

The human body has highly complex physiological mechanisms to ensure that its physiological functions remain stable and are able to respond to peak demands. Physiologists and other clinical scientists have discovered much about the detailed functioning of the body, but its overall control is often difficult to predict. This is where simulation techniques are helpful. Simulation allows physiological responses to be predicted, and then compared with actual clinical data. This enables different models to be assessed, and hence improves one´s understanding of the body´s control mechanisms. One example which researchers have considered, is that of blood pressure control. In the authors´ research, they have taken a published model for the control of blood pressure, discovered its limitations, and then improved the model so that it would more accurately predict actual clinical changes