Title :
Designing synthetic biological networks
Author :
Chen, Luonan ; Wang, Ruiqi ; Zhou, Xiabo ; Wong, Stephen
Author_Institution :
Osaka Sangyo Univ.
Abstract :
We aim to design and construct synthetic biological networks, such as gene switch or gene oscillator in this paper from the viewpoint of integrated systems biology. The theoretical results provide insights into the modular structures of gene regulatory networks and their quantitative functions. A hybrid feedback network is adopted to provide a variety of functional designs, which demonstrate the crucial role of interactions between biological modules
Keywords :
network synthesis; networks (circuits); biological module; gene oscillator; gene regulatory network; gene switch; hybrid feedback network; integrated system biology; modular structure; synthetic biological network; Biological system modeling; Biological systems; Chemicals; Delay effects; Feedback; Large-scale systems; Oscillators; Proteins; Switches; Systems biology;
Conference_Titel :
Circuits and Systems, 2006. ISCAS 2006. Proceedings. 2006 IEEE International Symposium on
Conference_Location :
Island of Kos
Print_ISBN :
0-7803-9389-9
DOI :
10.1109/ISCAS.2006.1693595