DocumentCode :
2552317
Title :
Analysis of the Topological Characteristics of a Protein-Protein Interaction Network
Author :
Sun, Yuanyuan ; Zhao, Yujie ; Tse, Chi K. ; Lau, Francis C M
Author_Institution :
Coll. of Comput. Sci. & Technol., DaLian Univ. of Technol., Dalian, China
fYear :
2012
fDate :
18-21 Oct. 2012
Firstpage :
127
Lastpage :
130
Abstract :
The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.
Keywords :
molecular biophysics; proteins; small-world networks; topology; PPI network; average path length; clustering coefficient; complex biological networks; complex networks; degree correlations; degree distribution; fractality; network diameter; protein-protein interaction network; scale-free distributions; small-world distributions; topological characteristics; Complex networks; Correlation; Educational institutions; Fractals; Niobium; Proteins; PPI networks; correlations; fractal; scale-free; small-world; topological analysis;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Chaos-Fractals Theories and Applications (IWCFTA), 2012 Fifth International Workshop on
Conference_Location :
Dalian
Print_ISBN :
978-1-4673-2825-8
Type :
conf
DOI :
10.1109/IWCFTA.2012.36
Filename :
6383260
Link To Document :
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