Title :
Optofluidic microsorter: an integrated flow cytometry instrument for cell biology applications
Author :
Marchand, Philippe ; Zhang, Haichuan ; Butler, William ; McNeeley, Patricia ; Diver, Jonathan
Author_Institution :
Celula Inc., San Diego, CA
Abstract :
The authors have built a high-throughput, fluorescence-activated microfluidic cell sorter based on an active, all-optical particle control switch. After being aligned to the center of the channel by flow focusing, cells are analyzed and then switched based on their detected fluorescence. Target cells are directed by the laser to the collection output while all other cells flow to the waste output
Keywords :
biological techniques; cellular transport; fluorescence; microchannel flow; optical switches; all-optical particle control switch; cell biology; flow focusing; fluorescence; integrated flow cytometry; optofluidic microsorter; Biological cells; Electrokinetics; Fluid flow control; High speed optical techniques; Instruments; Microfluidics; Optical buffering; Optical interconnections; Optical switches; Sorting;
Conference_Titel :
LEOS Summer Topical Meetings, 2006 Digest of the
Conference_Location :
Quebec City, Que.
Print_ISBN :
1-4244-0090-2
DOI :
10.1109/LEOSST.2006.1693957
