Title :
Toward, single molecule detection with photonic crystal microcavity biosensors
Author :
Mirkarimi, L.W. ; Zlatanovic, S. ; Sigalas, M.S. ; Bynum, M.A. ; Robotti, K. ; Chow, E. ; Grot, A.
Author_Institution :
Agilent Technol. Laboratories, Palo Alto, CA
Abstract :
Time resolved biomolecular binding events were measured using photonic crystal microcavity resonators integrated with microfluidics. The optical field is confined to a volume of 33 times 10-18 liters, which enables monitoring of single binding events
Keywords :
biosensors; microcavities; microfluidics; molecular biophysics; optical sensors; photonic crystals; microfluidics; photonic crystal microcavity biosensors; single binding; single molecule detection; time resolved biomolecular binding; Biosensors; Chemical and biological sensors; Microcavities; Microfluidics; Optical resonators; Optical sensors; Optical surface waves; Photonic crystals; Resonance; Surface treatment;
Conference_Titel :
LEOS Summer Topical Meetings, 2006 Digest of the
Conference_Location :
Quebec City, Que.
Print_ISBN :
1-4244-0090-2
DOI :
10.1109/LEOSST.2006.1693965
