Title :
Evaluation of time of flight (TOF) and point spread function (PSF) reconstructions in the quantification of myocardial blood flow with 13N ammonia and PET: Comparison among reconstructions (reprojection, OSEM), software (PMOD and CARIMAS) and operators
Author :
Presotto, Luca ; Busnardo, E. ; Bettinardi, V. ; Landoni, C. ; Todeschini, P. ; Rimoldi, O. ; Gilardi, M.C. ; Gianolli, L.
Author_Institution :
Dept. of Phys., Milano-Bicocca Univ., Milan, Italy
fDate :
Oct. 27 2012-Nov. 3 2012
Abstract :
Myocardial blood flow quantification with PET and 13NH3 is a well established technique to evaluate the coronary flow reserve in patient with different cardiomyopathies. We performed an in depth evaluation of the variation in the results when modifying the reconstruction technique (OSEM algorithms, analytical algorithms, OSEM algorithms including time of flight and point spread function modelling), when using different two different software implementing the same kinetic model (PMOD and CARIMAS) and we also evaluated the inter-operator variabilities with 2 operators.
Keywords :
cardiology; haemodynamics; haemorheology; image reconstruction; medical image processing; optical transfer function; positron emission tomography; time of flight spectra; CARIMAS software; OSEM algorithms; PMOD software; PSF reconstruction; ammonia; analytical algorithms; cardiomyopathies; inter-operator variability; myocardial blood flow quantification; point spread function modelling; time of flight evaluation;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2012 IEEE
Conference_Location :
Anaheim, CA
Print_ISBN :
978-1-4673-2028-3
DOI :
10.1109/NSSMIC.2012.6551912
