DocumentCode
2564927
Title
A memetic clustering algorithm for the functional partition of genes based on the gene ontology
Author
Speer, Nora ; Spieth, Christian ; Zell, Andrea
Author_Institution
Centre for Bioinformatics, Tubingen Univ., Germany
fYear
2004
fDate
7-8 Oct. 2004
Firstpage
252
Lastpage
259
Abstract
With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data the need of a functional grouping of genes arises. We propose a new clustering algorithm for the partition of genes or gene products according to their known biological function based on Gene Ontology terms. Ontologies offer a mechanism to capture knowledge in a shareable form that is also processable by computers. Our functional cluster algorithm promises to automatize, speed up and therefore improve biological data analysis.
Keywords
biology computing; data analysis; genetics; ontologies (artificial intelligence); statistical analysis; biological data analysis; biological function; capture knowledge; functional partition; gene ontology; memetic clustering algorithm; Bioinformatics; Biology computing; Clustering algorithms; DNA; Data analysis; Databases; Genomics; Ontologies; Partitioning algorithms; Throughput;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Intelligence in Bioinformatics and Computational Biology, 2004. CIBCB '04. Proceedings of the 2004 IEEE Symposium on
Print_ISBN
0-7803-8728-7
Type
conf
DOI
10.1109/CIBCB.2004.1393961
Filename
1393961
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