DocumentCode :
2564927
Title :
A memetic clustering algorithm for the functional partition of genes based on the gene ontology
Author :
Speer, Nora ; Spieth, Christian ; Zell, Andrea
Author_Institution :
Centre for Bioinformatics, Tubingen Univ., Germany
fYear :
2004
fDate :
7-8 Oct. 2004
Firstpage :
252
Lastpage :
259
Abstract :
With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data the need of a functional grouping of genes arises. We propose a new clustering algorithm for the partition of genes or gene products according to their known biological function based on Gene Ontology terms. Ontologies offer a mechanism to capture knowledge in a shareable form that is also processable by computers. Our functional cluster algorithm promises to automatize, speed up and therefore improve biological data analysis.
Keywords :
biology computing; data analysis; genetics; ontologies (artificial intelligence); statistical analysis; biological data analysis; biological function; capture knowledge; functional partition; gene ontology; memetic clustering algorithm; Bioinformatics; Biology computing; Clustering algorithms; DNA; Data analysis; Databases; Genomics; Ontologies; Partitioning algorithms; Throughput;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computational Intelligence in Bioinformatics and Computational Biology, 2004. CIBCB '04. Proceedings of the 2004 IEEE Symposium on
Print_ISBN :
0-7803-8728-7
Type :
conf
DOI :
10.1109/CIBCB.2004.1393961
Filename :
1393961
Link To Document :
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