Title :
Fully Electronic CMOS DNA Detection Array Based on Capacitance Measurement with On-Chip Analog-to-Digital Conversion
Author :
Stagni, C. ; Esposti, D. ; Guiducci, C. ; Paulus, C. ; Schienle, Meinrad ; Augustyniak, Marek ; Zuccheri, G. ; Samori, B. ; Benini, Luca ; Ricco, Bruno ; Thewes, Roland
Author_Institution :
Bologna Univ.
Abstract :
An 8 times 16 array of sensing micro-sites employs a fully-electrical label-free technique for DNA recognition using capacitance measurement and is fabricated in 0.5mum CMOS with added noble metal. Repeatability and parallel detection capability have been demonstrated. The DNA-chip is suitable for low-cost, fully-integrated point-of-care applications
Keywords :
CMOS integrated circuits; DNA; analogue-digital conversion; biological techniques; biomedical electronics; 0.5 micron; CMOS; DNA detection array; DNA recognition; capacitance measurement; on-chip analog-to-digital conversion; sensing micro-sites; Analog-digital conversion; Capacitance measurement; Chemical sensors; Circuits; DNA; Electrodes; Frequency; Proteins; Sensor arrays; Voltage;
Conference_Titel :
Solid-State Circuits Conference, 2006. ISSCC 2006. Digest of Technical Papers. IEEE International
Conference_Location :
San Francisco, CA
Print_ISBN :
1-4244-0079-1
DOI :
10.1109/ISSCC.2006.1696035
