A modified fast laser-Doppler flowmetry to measure the pulsatile microcirculation in rats

Author

Jan, Ming-Yie ; Hsiu, Hsin ; Wang, Yuh-Ying Lin ; Wang, Wei-Kung

Author_Institution

Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei, Taiwan

fYear

1998

fDate

29 Oct-1 Nov 1998

Firstpage

415

Abstract

A fast laser-Doppler flowmetry (LDF) is modified from a commercial one to measure the pulsatile microcirculation in rats. The time constant (TC) of the integrator in the analogue circuit of the LDF was modified; the frequency response of the modification was simulated by PSPICE to estimate the high 3 dB frequency. The coefficients of variance of 32 2-second ensembles of flux in the calibration standard measured by the commercial LDF and the modified one were less than 2%. The animal tests also clearly demonstrated the pulsatile microcirculation on the renal cortex in the rat

Keywords

Doppler measurement; blood flow measurement; covariance analysis; frequency response; laser applications in medicine; laser velocimetry; pulsatile flow; PSPICE simulation; animal tests; calibration standard; coefficients of variance; frequency response; integrator time constant; modified fast laser-Doppler flowmetry; pulsatile microcirculation measurement; rats; renal cortex; Animals; Brain modeling; Calibration; Circuit simulation; Frequency estimation; Frequency response; Integrated circuit measurements; Measurement standards; Rats; SPICE;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE

Conference_Location

Hong Kong

ISSN

1094-687X

Print_ISBN

0-7803-5164-9

Type

conf

DOI

10.1109/IEMBS.1998.745932

Filename

745932