The bioequivalence identification based on the situ data

To the traditional bioequivalent identification, the stringent requirements, limitations on the scope of inspection and the enormous waste of inspection resources are analyzed. The bioequivalent model of normal distribution is established perfectly by using statistical theory; the normal model of tested system about medium-sized samples is established by using information entropy method of no-statistics theory, the normal model of tested system about small-sized samples is established by using Bayesian method of no-statistics theory. In order to achieve the unified identification algorithm, the equivalent normal transforms of information distribution is quoted; all models are established and are calculated through VB Programming; Through analysis of the examples about traditional and normal method, we know that two bioequivalent identification methods is identity, but normal method is more simple, intuitive and easy to grasp than traditional method. The normal bioequivalent method can suit to broad and complex bioequivalence test, save various testing resources, reduce testing costs.