Title :
Mechanism of accelerated bone fracture healing
Author_Institution :
Sch. of Environ. Sci., Jawaharlal Nehru Univ., New Delhi, India
fDate :
29 Oct-1 Nov 1998
Abstract :
Electrical stimulation is generally though of as enhancing bone repair. However, the effects of these fields are, in part, determined by their are three methods in use for bone fracture repair. One is electrostimulation due to direct current, second is inductive coupling and finally capacitively coupling a radiofrequency field at the fracture site using a set of parallel plates. Low-frequency fields have been used for bone loss and to maintain bone mass in models of bone resorption by decreasing osteoclastic bone removal. Studies of the effects of these fields upon osteoclasts in vitro have shown a decrease in both osteoclastic differentiation and lysosomal enzyme content. Finally these fields have been shown to interfere with parathyroid hormone receptors
Keywords :
bioelectric phenomena; biological effects of fields; bone; cellular effects of radiation; electric field effects; fracture; accelerated bone fracture healing mechanism; bone loss; bone mass maintenance; bone repair enhancement; bone resorption models; capacitive coupling; direct current electrostimulation; inductive coupling; lysosomal enzyme content; osteoclast effects; osteoclastic bone removal decrease; osteoclastic differentiation; parallel plates; parathyroid hormone receptors; radiofrequency field; Animals; Biochemistry; Bones; Electrical stimulation; Electromagnetic fields; Electromagnetic radiation; Electronic mail; In vitro; Radio frequency; Rats;
Conference_Titel :
Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE
Conference_Location :
Hong Kong
Print_ISBN :
0-7803-5164-9
DOI :
10.1109/IEMBS.1998.746101