Title :
Deblurring of probabilistic ODFs in quantitative diffusion MRI
Author :
Tristán-Vega, Antonio ; Aja-Fernández, Santiago ; Westin, Carl-Fredrik
Author_Institution :
Lab. de Procesado de Imagen, Spain
Abstract :
The Funk-Radon Transform allows to approximate the central section integral of the diffusion signal to compute probabilistic Orientation Distribution Functions (ODF) of fiber populations, provided the behavior for the b-values not acquired is known. To relax the latter demand, it has been proposed to compute instead the integral inside the disk defined in the central section by the b-value acquired. The price to pay is low-pass filtering the ODF, cropping the information it provides. We propose a method to palliate this problem with negligible computational overload. Not only it improves the accuracy in the determination of the diffusion directions, but it also refines the crossing angles that can be resolved.
Keywords :
biodiffusion; biomedical MRI; data acquisition; filtering theory; low-pass filters; medical signal processing; probability; transforms; Funk-Radon transform; b-value acquisition; central section integral; diffusion signal; low-pass filtering; probabilistic orientation distribution function deblurring; quantitative diffusion MRI; Computational modeling; Convolution; Eigenvalues and eigenfunctions; Magnetic resonance imaging; Probabilistic logic; Tensile stress; Transforms; Diffusion MRI; HARDI; ODF; OPDT;
Conference_Titel :
Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on
Conference_Location :
Barcelona
Print_ISBN :
978-1-4577-1857-1
DOI :
10.1109/ISBI.2012.6235709