DocumentCode :
2572172
Title :
Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy
Author :
Bjerre, T. ; Fogtmann, M.O. ; Aznar, M. ; Munck af Rosenschold, P. ; Specht, L. ; Larsen, Rasmus
Author_Institution :
Dept. of Inf. & Math. Modelling, Image Anal. & Comput. Graphics, Tech. Univ. of Denmark, Lyngby, Denmark
fYear :
2012
fDate :
2-5 May 2012
Firstpage :
1224
Lastpage :
1227
Abstract :
For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.
Keywords :
cancer; computerised tomography; image registration; lung; medical image processing; radiation therapy; tumours; 4DCT breathing thorax POPI model; Hodgkin lymphoma; IGRT; bone rigidity; computed tomography scan deformable registration; contour propagation; gross tumor volume; image guided radiation therapy; image guided radiotherapy; local tissue volume change; lungs; post chemo CT scan registration; prechemo CT scan registration; spatially varying Riemannian elasticity regularization; spatially varying elasticity parameters; thoracic CT registration; Biological tissues; Bones; Computed tomography; Elasticity; Lungs; Planning; Tumors;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on
Conference_Location :
Barcelona
ISSN :
1945-7928
Print_ISBN :
978-1-4577-1857-1
Type :
conf
DOI :
10.1109/ISBI.2012.6235782
Filename :
6235782
Link To Document :
بازگشت