DocumentCode
2572523
Title
QuantWiz: A Parallel Software Package for LC-MS-based Label-Free Protein Quantification
Author
Wang, Jing ; Zhang, Yunquan ; Zhang, Xianyi ; Sun, Xiangzheng ; Hu, Zelin ; Li, Sujun ; Zeng, Rong
Author_Institution
Lab. of Parallel Comput., Chinese Acad. of Sci., Beijing, China
fYear
2009
fDate
25-27 June 2009
Firstpage
683
Lastpage
687
Abstract
Nowadays proteomics becomes more and more popular in life science. Protein quantification, especially based on mass spectrometry (short for MS) method, is perceived as an essential part of research on proteomics. There have been some algorithms and software for protein quantification based on MS. But they have difficulties on portability, applicability and longtime running. To solve these problems, we developed a new domestic parallel software package called QuantWiz for high performance liquid chromatography (short for LC)-MS-based label-free protein quantification. In this paper, we described the framework design and prototype development of this high performance software package firstly. Also, user interface developed for the visualization of QuantWiz is introduced. Finally, we showed implementation of the parallelization version and performance of some experiments on this software package.
Keywords
biology computing; mass spectroscopy; proteins; proteomics; software packages; LC-MS-based label-free protein quantification; QuantWiz; liquid chromatography; mass spectrometry method; parallel software package; proteomics; Biology; Laboratories; Mass spectroscopy; Peptides; Proteins; Proteomics; Software algorithms; Software design; Software packages; Throughput; abundance ratio; label-free; mass spectrometry; parallelization; protein quantification;
fLanguage
English
Publisher
ieee
Conference_Titel
High Performance Computing and Communications, 2009. HPCC '09. 11th IEEE International Conference on
Conference_Location
Seoul
Print_ISBN
978-1-4244-4600-1
Electronic_ISBN
978-0-7695-3738-2
Type
conf
DOI
10.1109/HPCC.2009.62
Filename
5167064
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