DocumentCode
2580550
Title
Control cell behavior on physical topographical surface
Author
Su, Wen-Ta ; Chu, I-Ming ; Yang, Jung-Yen ; Huang, Chun-Kai
Author_Institution
Dept. of Chem. Eng., Nat. Taipei Univ. of Technol., Hsinchu, Taiwan
fYear
2003
fDate
29-31 Oct. 2003
Firstpage
218
Lastpage
219
Abstract
Topographical cues, independent of biochemistry, generated by the PDMS substrate may have significant effects on cellular behavior. Mouse bone marrow stromal fibroblasts were examined on grooved substrata of equal groove and ridge width (30 /spl mu/m depth). It was found that the topographical surface had an effect in determining cell alignment and migration.
Keywords
bone; cell motility; cellular biophysics; polymers; surface topography; 30 micron; PDMS substrate; biochemistry; cell alignment; cell migration; cell properties; control cell behavior; grooved substrata; mouse bone marrow stromal fibroblasts; physical topographical surface; polydimethylsiloxanes; Adhesives; Bones; Cells (biology); Chemical engineering; Chemical technology; Fibroblasts; Mice; Surface morphology; Surface texture; Surface topography;
fLanguage
English
Publisher
ieee
Conference_Titel
Microprocesses and Nanotechnology Conference, 2003. Digest of Papers. 2003 International
Conference_Location
Tokyo, Japan
Print_ISBN
4-89114-040-2
Type
conf
DOI
10.1109/IMNC.2003.1268720
Filename
1268720
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