Numerical simulation of heat transfer for the treatment of in-stent restenosis with a heatable metal stent

Based on the analysis of biological heat transfer for the hyperthermia of in-stent restenosis (ISR) with a heating vascular stent, the three-dimension heat transfer model has been established with the N-S equation and the equation of Pennes bio-heat transfer as a mathematical model. And the three-dimension transient temperature distribution has been calculated considering the blood flow field and temperature field coupling. Simulations are performed to examine the effects of a variety of thermal parameters, such as heating power, blood flow rate and thermal conductivity on the temperature distribution in tissues. The results show that blood flow causes a significant cooling effect during the heating. The temperature distribution is sensitive to heating power and blood flow rate, but relatively insensitive to the tissue thermal conductivity.