Title :
Electrowetting-based on-chip sample processing for integrated microfluidics
Author :
Fair, R.B. ; Srinivasan, V. ; Ren, H. ; Paik, P. ; Pamula, V.K. ; Pollack, M.G.
Author_Institution :
Dept. of Electr. & Comput. Eng., Duke Univ., Durham, NC, USA
Abstract :
In this work, results and data are reported on key aspects of sample processing protocols performed on-chip in a digital microfluidic lab-on-a-chip. We report the results of experiments on aspects of sample processing, including on-chip preconcentration and dilution, on-chip sample injection or dispensing, and sample mixing. It is shown that high speed transport and mixing of analytes and reagents can be performed using biological solutions without system contamination.
Keywords :
biomedical electronics; microfluidics; mixing; specimen preparation; wetting; analytes; biological solutions; digital microfluidic lab-on-a-chip; dilution; dispensing; electrowetting; high speed transport; integrated microfluidics; mixing; on-chip preconcentration; on-chip sample processing; reagents; sample injection; sample processing protocols; system contamination; Clocks; Electrodes; Instruments; Laboratories; Metal-insulator structures; Microfluidics; Performance analysis; Protocols; Robots; Threshold voltage;
Conference_Titel :
Electron Devices Meeting, 2003. IEDM '03 Technical Digest. IEEE International
Conference_Location :
Washington, DC, USA
Print_ISBN :
0-7803-7872-5
DOI :
10.1109/IEDM.2003.1269396