Title :
Label-free low-cost disposable DNA hybridization detection systems using organic TFTs
Author :
Zhang, Qintao ; Subramanian, Vivek
Author_Institution :
Univ. of California, Berkeley
Abstract :
We report an OTFT-based label-free DNA hybridization detection system integrating electrically-read DNA hybridization sensors and microfluidic delivery channels. We use DNA-doped OTFTs as electrically-read DNA sensors. By integrating with polymer microfluidics, for the first time, we demonstrate the technologies required to realize disposable, rapid turn-around tools for field-deployable genetic diagnosis.
Keywords :
DNA; bioMEMS; biomedical electronics; biosensors; genetics; microfluidics; molecular biophysics; organic semiconductors; patient diagnosis; polymers; thin film sensors; thin film transistors; disposable DNA hybridization detection systems; electrically-read DNA hybridization sensors; field-deployable genetic diagnosis tool; microfluidic delivery channels; organic TFT; polymer microfluidics; Biomedical imaging; DNA; Diseases; Genetics; Medical diagnostic imaging; Microfluidics; Organic thin film transistors; Pentacene; Sensor systems; Thin film transistors;
Conference_Titel :
Electron Devices Meeting, 2007. IEDM 2007. IEEE International
Conference_Location :
Washington, DC
Print_ISBN :
978-1-4244-1507-6
Electronic_ISBN :
978-1-4244-1508-3
DOI :
10.1109/IEDM.2007.4418909
