MR imaging of Fe-Co nanoparticles, magnetotactic bacteria and Fe3O4 microparticles for future drug delivery applications

Author

Felfoul, Ouajdi ; Pouponneau, Pierre ; Mathieu, Jean-Baptiste ; Martel, Sylvain

Author_Institution

Dept. of Comput. Eng. & Inst. of Biomed. Eng., Campus of the Univ. de Montreal, Montreal, QC

fYear

2007

fDate

2-5 Aug. 2007

Firstpage

308

Lastpage

311

Abstract

Magnetic resonance imaging characteristics of novel potential drug delivery agents are investigated. Candidate carriers considered in this study are iron-cobalt (Fe-Co) nanoparticles, magnetotactic bacteria (MTB), and magnetite (Fe₃O₄) microparticles. The micro and nanoparticles are highly magnetic and can be steered using gradient coils. MTB, on the other hand, are microorganisms that naturally follow the magnetic field lines through a mechanism called magnetotaxis. These carriers share the capability to be controlled by magnetic field and to be detected on MR images.

Keywords

biomedical materials; cobalt alloys; drug delivery systems; iron alloys; iron compounds; magnetic particles; magnetic resonance imaging; microorganisms; nanobiotechnology; nanoparticles; Fe₃O₄; FeCo; drug delivery applications; iron-cobalt nanoparticles; magnetic resonance imaging; magnetite microparticles; magnetotactic bacteria; magnetotaxis; microorganisms; potential drug delivery agents; Biomedical imaging; Drug delivery; Laboratories; Magnetic fields; Magnetic levitation; Magnetic materials; Magnetic particles; Magnetic resonance imaging; Microorganisms; Nanoparticles; Fe-Co nanoparticles; Fe3O4 microparticles; MR imaging; drug delivery; magnetotactic bacteria;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanotechnology, 2007. IEEE-NANO 2007. 7th IEEE Conference on

Conference_Location

Hong Kong

Print_ISBN

978-1-4244-0607-4

Electronic_ISBN

978-1-4244-0608-1

Type

conf

DOI

10.1109/NANO.2007.4601196

Filename

4601196