Title :
MR imaging of Fe-Co nanoparticles, magnetotactic bacteria and Fe3O4 microparticles for future drug delivery applications
Author :
Felfoul, Ouajdi ; Pouponneau, Pierre ; Mathieu, Jean-Baptiste ; Martel, Sylvain
Author_Institution :
Dept. of Comput. Eng. & Inst. of Biomed. Eng., Campus of the Univ. de Montreal, Montreal, QC
Abstract :
Magnetic resonance imaging characteristics of novel potential drug delivery agents are investigated. Candidate carriers considered in this study are iron-cobalt (Fe-Co) nanoparticles, magnetotactic bacteria (MTB), and magnetite (Fe3O4) microparticles. The micro and nanoparticles are highly magnetic and can be steered using gradient coils. MTB, on the other hand, are microorganisms that naturally follow the magnetic field lines through a mechanism called magnetotaxis. These carriers share the capability to be controlled by magnetic field and to be detected on MR images.
Keywords :
biomedical materials; cobalt alloys; drug delivery systems; iron alloys; iron compounds; magnetic particles; magnetic resonance imaging; microorganisms; nanobiotechnology; nanoparticles; Fe3O4; FeCo; drug delivery applications; iron-cobalt nanoparticles; magnetic resonance imaging; magnetite microparticles; magnetotactic bacteria; magnetotaxis; microorganisms; potential drug delivery agents; Biomedical imaging; Drug delivery; Laboratories; Magnetic fields; Magnetic levitation; Magnetic materials; Magnetic particles; Magnetic resonance imaging; Microorganisms; Nanoparticles; Fe-Co nanoparticles; Fe3O4 microparticles; MR imaging; drug delivery; magnetotactic bacteria;
Conference_Titel :
Nanotechnology, 2007. IEEE-NANO 2007. 7th IEEE Conference on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-0607-4
Electronic_ISBN :
978-1-4244-0608-1
DOI :
10.1109/NANO.2007.4601196
