Title :
Modelling O2 and CO2 dissociation curves of newborn infants
Author :
Lynch, Elizabeth A. ; Waggener, Thomas B.
Author_Institution :
Dept. of Biomed. Eng., Boston Univ., MA, USA
Abstract :
In order to study gas exchange and respiratory control system stability in the newborn period, a model of the O2 and CO2 dissociation curves is developed which incorporates the changes in hemoglobin with age. The model is a modification of Grodin´s equations. The dissociation curves generated by the computer model take into account hematocrit, bicarbonate concentration, pH, barometric pressure, the Bohr effect, the Haldane effect, and the effect of postnatal age on hemoglobin type. They provide improved accuracy in modeling gas exchange and respiratory control system stability in infants
Keywords :
biocontrol; blood; physiological models; Bohr effect; CO2; Grodin´s equations; Haldane effect; O2; barometric pressure; bicarbonate concentration; computer model; dissociation curves; gas exchange modeling; hemoglobin; newborn infants; pH; postnatal age; respiratory control system stability; Blood; Equations; High definition video; Pediatrics; Stability;
Conference_Titel :
Bioengineering Conference, 1991., Proceedings of the 1991 IEEE Seventeenth Annual Northeast
Conference_Location :
Hartford, CT
Print_ISBN :
0-7803-0030-0
DOI :
10.1109/NEBC.1991.154585
