Title :
Impedance mapping of myocardial tissue during ischemia
Author :
Mirotznik, Mark S. ; Fallert, Michael A. ; Bogen, Daniel K. ; Foster, Kenneth R.
Author_Institution :
Dept. of Bioeng., Pennsylvania Univ., Philadelphia, PA, USA
Abstract :
An impedance measurement system was developed for measuring myocardial tissue impedance (MTI) during ischemia in sheep and epicardial mapping system was developed that used a four electrode method with cardiac cycle gated and signal averaged measurements. After 60 minutes of ischemia, MTI increased by an average of 200% compared to non-ischemic tissue. A myocardial tissue model was developed which suggests that changes in MTI are primarily due to changes in cellular volume fraction
Keywords :
bioelectric phenomena; biological techniques and instruments; cardiology; electric impedance measurement; muscle; 4-electrode method; 60 min; cardiac cycle gating; cellular volume fraction; epicardial mapping system; impedance mapping; impedance measurement system; ischemia; myocardial tissue; sheep; signal averaged measurements; Band pass filters; Conductivity; Current measurement; Electrodes; Frequency; Impedance measurement; Ischemic pain; Myocardium; Permittivity; Voltage;
Conference_Titel :
Bioengineering Conference, 1991., Proceedings of the 1991 IEEE Seventeenth Annual Northeast
Conference_Location :
Hartford, CT
Print_ISBN :
0-7803-0030-0
DOI :
10.1109/NEBC.1991.154640
