FDTD-based temperature distribution computation of microwave hyperthermia for breast cancer

A three dimensional (3D) breast model, which contained four different media: skin, fat, tumor, and deionized water (as cooling medium around the breast), was build for finite-difference time-domain (FDTD) computations in this study. The computations of electromagnetic fields and temperature distributions were used FDTD method and finite-difference approximation respectively. The Pennes bioheat equation (PBHE) was used to solve the 3D temperature distributions. Optimizing the hyperthermia antenna array based on the temperature distributions, we can obtain more effective hyperthermia.